Metabolomics – Basic Concepts, Strategies and Methodologies

Authors

  • Jindra Musilová Department of Biochemistry, Faculty of Science and Central European Technology Institute, Masaryk University, Brno
  • Zdeněk Glatz Department of Biochemistry, Faculty of Science and Central European Technology Institute, Masaryk University, Brno

Keywords:

metabolomics, metabolome, metabolism, nuclear magnetic resonance, mass spectrometry, gas chromatography, liquid chromatography, capillary electrophoresis

Abstract

This review defines metabolomics and clarifies its history and significance. Various strategies of metabolo­mics research are described together with their main application fields. The review focuses on the methods of sample preparation and on the analytical methodologies that are most frequently used in metabolomic studies - NMR, MS, GC/MS, HPLC/MS and CE/MS. Practical importance of metabolomics and its role in system biology are mentioned as well.

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Published

2011-10-15

How to Cite

Musilová, J., & Glatz, Z. (2011). Metabolomics – Basic Concepts, Strategies and Methodologies. Chemické Listy, 105(10), 745–751. Retrieved from http://ww-w.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1039

Issue

Vol. 105 No. 10 (2011)

Section

Articles