Retroviral Genome and Physiological Function of Its Products

Authors

  • P. Strnad Department of Biochemistry and Microbiology and Center for Integrated Genomics, Institute of Chemical Technology, Prague
  • S. Haubova Department of Biochemistry and Microbiology and Center for Integrated Genomics, Institute of Chemical Technology, Prague
  • T. Ruml Department of Biochemistry and Microbiology and Center for Integrated Genomics, Institute of Chemical Technology, Prague

Abstract

Retroviridae comprise viruses with diploid RNA genome, which are replicatedby RNA-dependent DNA polymerase, i.e. reverse transcriptase. This enzyme itself is a valuable tool of molecular biology. However, retroviruses are in the forefront of scientific interest mainly due to the serious diseases they cause. In addition, elucidation of some aspects of the cell cycle andcell ular oncogens originated from the studies of retroviral oncogenesis. Another attractive area is the design of retroviral vectors for gene therapies. This review attempts to sum up the most recent general knowledge of the function of retroviral genes and their products in the virus life cycle.

Published

2003-10-15

How to Cite

Strnad, P., Haubova, S., & Ruml, T. (2003). Retroviral Genome and Physiological Function of Its Products. Chemické Listy, 97(9). Retrieved from http://ww-w.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/2221

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