Voltammetric Determination of Diazepam – A Comprehensive Review

The publication is dedicated to Prof. RNDr. Jiří Barek, CSc. on the occasion of his jubilee

Authors

  • Soňa Slašťanová Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Bratislava, Slovakia
  • Adela Kekeľáková Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Bratislava, Slovakia
  • Marek Haššo Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Bratislava, Slovakia
  • Ľubomír Švorc Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Bratislava, Slovakia https://orcid.org/0000-0002-9588-8609

DOI:

https://doi.org/10.54779/chl20240507

Keywords:

benzodiazepine, diazepam, electroanalytical determination, voltammetry

Abstract

The review deals with the fundamental characteristics of an important biologically active substance – diazepam, summarizing voltammetric methods for its determination in various samples. This 1,4-benzodiazepine derivative is used as an adjunct to treat anxiety associated with psychiatric illnesses (e.g. schizophrenia). Due to the increasing number of forensic cases related to overdose of diazepam (often in combination with alcohol), the development of rapid and reliable analytical methods for its detection and determination in pharmaceutical samples and alcoholic drinks is an important goal of analysts. In this review, an overview of the voltammetric methods to determine diazepam in various samples is briefly summarized.

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Published

2024-10-15

How to Cite

Slašťanová, S., Kekeľáková, A., Haššo, M., & Švorc, Ľubomír. (2024). Voltammetric Determination of Diazepam – A Comprehensive Review: The publication is dedicated to Prof. RNDr. Jiří Barek, CSc. on the occasion of his jubilee. Chemické Listy, 118(10), 507–514. https://doi.org/10.54779/chl20240507

Issue

Vol. 118 No. 10 (2024)

Section

Articles